LRP3 and GGA1

Data Source:
HPRD (two hybrid, in vitro)

		LRP3	GGA1
Description		LDL receptor related protein 3	golgi associated, gamma adaptin ear containing, ARF binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Clathrin-coated Pit Integral Component Of Membrane	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function		Molecular_function Protein Binding Small GTPase Binding
	Biological Process	Receptor-mediated Endocytosis Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Transport Across Blood-brain Barrier	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane
Pathways			TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433)	Health literacy ( 31250787)
Interacting Genes		3 interacting genes: GGA1 GGA2 MTNR1A	40 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR F8 GGA2 GGA3 IGF2R ING5 LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18
Entrez ID		4037	26088
HPRD ID		04406	12078
Ensembl ID		ENSG00000130881	ENSG00000100083
Uniprot IDs		O75074	Q9UJY5
PDB IDs			1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
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