UFSP1 and COG6

Data Source:
BioGRID (two hybrid)

		UFSP1	COG6
Description		UFM1 specific peptidase 1 (inactive)	component of oligomeric golgi complex 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Glycosylation
Pathways			COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Resting heart rate ( 29769521 27798624 20639392)	Asthma ( 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Height ( 31562340) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Psoriasis ( 25903422 18369459) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		42 interacting genes: C10orf55 CIDEB CIDEC COG6 CREB5 CSTF2 FAM222B FANCL FOXH1 FOXI1 GLYCTK GPSM3 HNF1B HOXC9 HSF4 INCA1 KRTAP15-1 LASP1 MSRB3 MYOZ3 PITX1 PITX2 POGZ POU6F2 PROP1 PRR22 RAPGEF3 RBPMS2 RUSC1 SMARCC1 SNRPC SPG21 TBX3 TCF7L2 TLX3 UBQLN2 VAC14 VAX2 VGLL3 VPS37C WWOX ZIC1	66 interacting genes: ARHGEF5 ATXN7 BAIAP2 BCL10 CCDC116 CCDC120 CCDC187 CCDC92 CCHCR1 CNN1 CNNM3 CSRP2 CUL5 DOCK8 DTNB FAM110A FAM90A1 FANCG FNDC11 GAS8 GEM GOLGA2 GRAP2 IGFN1 KANK2 LGALS14 LMO4 MCM7 MFAP1 MRI1 NDUFA5 NEK6 NTAQ1 NUP58 OAS1 PLEKHA2 POM121 PPP1R18 PPP1R32 PSMA1 PSMB1 QARS1 RAB3IL1 RAB6B RSPH14 RTP5 RUNX1T1 SCNM1 SMARCD1 SNAI1 SNAP29 SNRPB SPG21 SYCP2L SYT17 TBC1D22B TMSB4X TSGA10 TSHZ3 TSNAX TTC7B UFSP1 WASHC3 ZBTB16 ZFC3H1 ZNF417
Entrez ID		402682	57511
HPRD ID		18630	08445
Ensembl ID		ENSG00000176125	ENSG00000133103
Uniprot IDs		Q6NVU6	A0A024RDW5 A0A140VJG7 Q9Y2V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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