SOHLH1 and HEMK1

Data Source:
BioGRID (two hybrid)

		SOHLH1	HEMK1
Description		spermatogenesis and oogenesis specific basic helix-loop-helix 1	HemK methyltransferase family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Mitochondrion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Oocyte Differentiation Cell Differentiation	DNA Methylation Protein Methylation
Pathways
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)
Interacting Genes		26 interacting genes: ACTN3 ARID5A C10orf55 CASP3 CERCAM CTAG1A CTAG1B DTX2 FAM222B HEMK1 IL16 KRTAP19-5 NUP54 OIP5 PEF1 PFDN5 PRKAA2 PSMB4 RUSC1 STH SUOX TENT5B TLE5 TRAF1 USHBP1 ZMYND12	18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2
Entrez ID		402381	51409
HPRD ID		16678	13645
Ensembl ID		ENSG00000165643	ENSG00000114735
Uniprot IDs		Q5JUK2	A0A140VK98 B2RA37 Q9Y5R4
PDB IDs
Enriched GO Terms of Interacting Partners?
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