LGALS8 and TNFRSF18

Data Source:
BioGRID (affinity chromatography technology)

		LGALS8	TNFRSF18
Description		galectin 8	TNF receptor superfamily member 18
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Positive Regulation Of Leukocyte Migration Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Apoptotic Process Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Cell Adhesion
Pathways			TNFs bind their physiological receptors RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Drugs
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Inflammatory bowel disease ( 23128233)
Interacting Genes		20 interacting genes: APEH BARD1 CALCOCO2 ERBB2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 TAX1BP1 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2	6 interacting genes: LNX1 TNFSF18 TRAF1 TRAF2 TRAF3 UBQLN2
Entrez ID		3964	8784
HPRD ID		09356	04879
Ensembl ID		ENSG00000116977	ENSG00000186891
Uniprot IDs		O00214	A0A0R7FDM1 Q9Y5U5
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z
Enriched GO Terms of Interacting Partners?
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