STMN1 and UHMK1

Data Source:
HPRD (in vivo, two hybrid)

		STMN1	UHMK1
Description		stathmin 1	U2AF homology motif kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Membrane Neuron Projection Extracellular Exosome	Nucleus Nucleoplasm Golgi Apparatus Axon Midbody Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule
	Molecular Function	Protein Binding Tubulin Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Mitotic Cytokinesis Microtubule Depolymerization Mitotic Spindle Organization Signal Transduction Axonogenesis Brain Development Response To Virus Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Negative Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Negative Regulation Of Stress Fiber Assembly Establishment Of Skin Barrier Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Cell Cycle Arrest Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Protein Autophosphorylation Regulation Of Protein Export From Nucleus
Pathways		Nuclear signaling by ERBB4	Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS			Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)
Interacting Genes		17 interacting genes: CAMK2G CDK1 CDKN1B CHEK2 CSNK2A1 ERBB2 FANCC GLP1R HSPA5 HSPA8 MAPK3 PRKACA SEPTIN2 SESTD1 STAT3 UBQLN4 UHMK1	9 interacting genes: C1orf109 DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP
Entrez ID		3925	127933
HPRD ID		01047	12318
Ensembl ID		ENSG00000117632	ENSG00000152332
Uniprot IDs		A0A140VJW2 P16949	Q8TAS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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