RHOC and RIPOR3

Data Source:
BioGRID (two hybrid)

		RHOC	RIPOR3
Description		ras homolog family member C	RIPOR family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cleavage Furrow Stereocilium Cell Projection Neuron Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Positive Regulation Of Cell Migration Cortical Cytoskeleton Organization Positive Regulation Of Protein-containing Complex Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apical Junction Assembly Wound Healing, Spreading Of Cells Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Lipase Activity Skeletal Muscle Satellite Cell Migration
Pathways		Rho GTPase cycle G alpha (12/13) signalling events Sema4D induced cell migration and growth-cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases Activate ROCKs RHO GTPases Activate Formins RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate (creatinine) ( 28452372) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: ARHGAP1 CAV1 CIT DIAPH1 RIPOR2 RIPOR3 ROCK1 RTKN	6 interacting genes: CCDC125 RHOA RHOC SCML4 SHANK2 TRAF1
Entrez ID		389	140876
HPRD ID		01322	12757
Ensembl ID		ENSG00000155366	ENSG00000042062
Uniprot IDs		A0A024R0C8 P08134	A0A499FJE4 B7Z3F0 B7Z5S0 Q96MK2
PDB IDs		1Z2C 2GCN 2GCO 2GCP
Enriched GO Terms of Interacting Partners?
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