KMT5A and FAM9A

Data Source:
BioGRID (two hybrid)

		KMT5A	FAM9A
Description		lysine methyltransferase 5A	family with sequence similarity 9 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Cytosol	Synaptonemal Complex Nucleolus
	Molecular Function	P53 Binding Transcription Corepressor Activity Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific)	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Peptidyl-lysine Monomethylation Histone H4-K20 Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription, DNA-templated Cell Division Regulation Of Signal Transduction By P53 Class Mediator	Spermatid Development Meiotic Cell Cycle
Pathways		Condensation of Prophase Chromosomes PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) High density lipoprotein cholesterol levels ( 29403010)	Age at voice drop ( 27182965) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)
Interacting Genes		11 interacting genes: BTRC DTL E2F2 FAM9A H4-16 PCNA TCF7L2 TP53 TWIST1 UBE2I USP17L2	39 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 MLLT3 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775
Entrez ID		387893	171482
HPRD ID		06254	06506
Ensembl ID		ENSG00000183955	ENSG00000183304
Uniprot IDs		E3VVS3 Q9NQR1	Q8IZU1
PDB IDs		1ZKK 2BQZ 3F9W 3F9X 3F9Y 3F9Z 4IJ8 5HQ2 5T5G 5TEG 5TH7 5V2N 5W1Y 6BOZ
Enriched GO Terms of Interacting Partners?
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