NPSR1 and TMED10

Data Source:
BioGRID (two hybrid)

		NPSR1	TMED10
Description		neuropeptide S receptor 1	transmembrane p24 trafficking protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Gamma-secretase Complex
	Molecular Function	Vasopressin Receptor Activity Neuropeptide Receptor Activity	Protein Binding Protein Transmembrane Transporter Activity Syntaxin Binding Protein-containing Complex Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Kidney Development Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Interleukin-1 Production Vesicle Cargo Loading COPI-coated Vesicle Budding Response To Alkaloid Regulated Exocytosis Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Positive Regulation Of Protein Secretion Protein Transmembrane Transport Protein Localization To ERGIC Cytosol To ERGIC Protein Transport Regulation Of Amyloid-beta Formation Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Halothane
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)	Coronary artery disease ( 32469254) Heel bone mineral density ( 30598549) Height ( 19343178) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 MFSD10 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 TERF2IP TMED10 TMEM101	20 interacting genes: APH1A ARCN1 ARF1 CDC42 COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 DHODH FBXO7 GORASP2 NCSTN NPSR1 PSENEN SEC23B SLC13A1 TMED2
Entrez ID		387129	10972
HPRD ID		10547	12013
Ensembl ID		ENSG00000187258	ENSG00000170348
Uniprot IDs		A0A090N8Z1 Q6W5P4	A0A024R6I3 P49755
PDB IDs
Enriched GO Terms of Interacting Partners?
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