TMED10 and SEC23B

Data Source:
BioGRID (unspecified method)

		TMED10	SEC23B
Description		transmembrane p24 trafficking protein 10	SEC23 homolog B, COPII coat complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Gamma-secretase Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Syntaxin Binding Protein-containing Complex Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Kidney Development Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Interleukin-1 Production Vesicle Cargo Loading COPI-coated Vesicle Budding Response To Alkaloid Regulated Exocytosis Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Positive Regulation Of Protein Secretion Protein Transmembrane Transport Protein Localization To ERGIC Cytosol To ERGIC Protein Transport Regulation Of Amyloid-beta Formation Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity COPII-coated Vesicle Cargo Loading
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Coronary artery disease ( 32469254) Heel bone mineral density ( 30598549) Height ( 19343178) Refractive error ( 32231278)	Refractive error ( 32231278)
Interacting Genes		20 interacting genes: APH1A ARCN1 ARF1 CDC42 COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 DHODH FBXO7 GORASP2 NCSTN NPSR1 PSENEN SEC23B SLC13A1 TMED2	25 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 RIN1 SEC23A SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UGT1A1
Entrez ID		10972	10483
HPRD ID		12013	11543
Ensembl ID		ENSG00000170348	ENSG00000101310
Uniprot IDs		A0A024R6I3 P49755	A0A2R8YFH5 Q15437
PDB IDs
Enriched GO Terms of Interacting Partners?
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