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BEX2 and AKAP9
Data Source:
BioGRID
(two hybrid)
BEX2
AKAP9
Description
brain expressed X-linked 2
A-kinase anchoring protein 9
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Golgi Stack
Cis-Golgi Network
Centrosome
Cytosol
Cytoskeleton
Voltage-gated Potassium Channel Complex
Intracellular Membrane-bounded Organelle
Synaptic Membrane
Glutamatergic Synapse
Molecular Function
Signaling Receptor Binding
Protein Binding
DNA Binding
Signaling Receptor Binding
Protein Binding
Potassium Channel Regulator Activity
Protein Kinase A Regulatory Subunit Binding
Ion Channel Binding
Molecular Adaptor Activity
Biological Process
Apoptotic Process
Cell Cycle
Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Microtubule Nucleation
Signal Transduction
Chemical Synaptic Transmission
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Microtubule Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Maintenance Of Centrosome Location
Regulation Of Membrane Repolarization
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Cardiac Conduction
Cellular Response To CAMP
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Golgi Organization
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Anchoring of the basal body to the plasma membrane
Signaling by BRAF and RAF fusions
AURKA Activation by TPX2
Drugs
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) (
24236485
)
Breast cancer (
29059683
)
Cerebrospinal fluid p-tau levels in mild cognitive impairment (
29274321
)
Cerebrospinal fluid t-tau levels in mild cognitive impairment (
29274321
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Red blood cell count (
32888494
)
Interacting Genes
92 interacting genes:
AKAP9
AURKA
BCAR3
BHLHB9
BLZF1
BORCS6
BRMS1
CALCOCO2
CCDC197
CCDC57
CCDC85B
CCDC88B
CDR2
CEP70
COG4
CTAG1A
CTAG1B
CYSRT1
EXOC8
FGFR2
FSD2
FST
HSF2BP
HSPB2
HSPB2-C11orf52
KLHL20
KNSTRN
KRT15
KRT19
KRT27
KRT31
KRT34
KRT38
KRT39
KRT40
KRT6A
KRT75
KRTAP10-8
KRTAP11-1
KRTAP12-2
KRTAP2-3
KRTAP2-4
KRTAP21-2
KRTAP3-3
KRTAP4-12
KRTAP5-9
KRTAP6-2
KRTAP6-3
LCN2
LDOC1
LMO2
LZTS2
MAGEA11
MAGEA2
MAGEA2B
MAGEA4
MDFI
MIPOL1
MKRN3
MORN3
MRPL38
MSS51
MTUS2
NECAB2
NFKBID
OIP5
OMP
PIK3CA
PLA2G10
PLEKHG4
PNMA1
PPM1D
PRDM14
PTPN11
ROPN1L
SERTAD3
SPRED1
SPRY3
SSX2IP
SYCE1
TACC3
TRAF1
TRAF2
TRIM27
TRIM42
TRIM69
TRIM73
TRIP6
USHBP1
VPS28
ZDHHC17
ZNF19
85 interacting genes:
ABI2
BEX2
BLZF1
C1orf94
CALM1
CALM2
CALM3
CASK
CCDC116
CCDC146
CCP110
CDC5L
CEP55
CLIC1
CSNK1D
CSNK1E
CTBP1
CTNNA3
DVL2
FAM90A1
FMR1
FNBP1
FXR2
GLIS2
GPC4
GRIN1
GTSE1
HDDC3
HNRNPM
IKZF3
KCNQ1
KDM1A
KIF19
KLC4
LMO1
MAGEA6
MAGED1
MED1
MYO5A
NDEL1
PARD6G
PCM1
PCNT
PKN1
PKP2
PPP1CA
PPP2R1B
PPP2R3A
PRC1
PRDM14
PRKAR2A
PRKAR2B
PRKCE
RBM10
RBM14
RPA2
RSRC2
SAMD3
SCNM1
SF3B2
SLAIN1
SNF8
SNRPB
SSX2
SSX3
SSX5
SUV39H2
TACC3
TCEANC
TDP2
TENT5B
THAP1
THOC1
TLX3
TNIK
TRIP10
TSG101
TSNAX
TUBGCP3
TULP3
USHBP1
USO1
VPS9D1
WAC
YWHAE
Entrez ID
84707
10142
HPRD ID
06484
04921
Ensembl ID
ENSG00000133134
ENSG00000127914
Uniprot IDs
Q9BXY8
Q5GIA7
Q6PJH3
Q99996
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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