KPNA4 and CSE1L

Data Source:
BioGRID (pull down)

		KPNA4	CSE1L
Description		karyopherin subunit alpha 4	chromosome segregation 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process	Protein Import Into Nucleus Protein Export From Nucleus
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Attention deficit hyperactivity disorder ( 32279069) Bipolar disorder ( 31043756) Malaria ( 31844061) Myeloproliferative neoplasms ( 33057200) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smooth-surface caries ( 24556642) Total cholesterol levels ( 30275531)	Anger ( 24489884) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Non-response to citalopram or escitalopram and depression ( 27622933) Response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468) Subjective well-being ( 27089181)
Interacting Genes		26 interacting genes: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 FAM50B GTF2IRD1 HIF1A HNRNPC HSD3B7 KAT5 KPNB1 MAT2B MTA1 NCBP3 NTRK3 NUP50 PLAA RAC1 RCC1 RECQL TGM2 TP53 WT1	20 interacting genes: BIRC2 CDC42 CDH1 DUX4 HNRNPL KPNA1 KPNA2 KPNA4 KPNA6 KPNB1 MAPK6 MTNR1B PPP5C RAN RPL22 STAT1 SUMO2 TMEM62 YWHAG YWHAQ
Entrez ID		3840	1434
HPRD ID		04275	03217
Ensembl ID		ENSG00000186432	ENSG00000124207
Uniprot IDs		O00629	A0A384NKW7 P55060
PDB IDs		4UAE 5TBK 5XZX 6BVV 6BVZ 6BW9 6BWA 6BWB 6WX8 7JJL
Enriched GO Terms of Interacting Partners?
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