KNG1 and PLG

KNG1

PLG

Description kininogen 1 plasminogen
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging ( 22773346)
  • Blood protein levels ( 29875488 28240269)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Childhood ear infection ( 27182965 28928442)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Coronary artery disease ( 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • End stage renal disease x APOL1 genotype interaction ( 29885931)
  • Giant cell arteritis ( 28041642)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lipoprotein (a) levels ( 26377243)
  • Lipoprotein (a) levels in response to niacin in statin-treated individuals ( 30371334)
  • Lp (a) levels ( 21900290)
  • Myocardial infarction ( 26343387)
  • Plasma plasminogen levels ( 25208887)
  • Platelet count ( 32888494)
  • Triglyceride levels ( 32203549)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 28 interacting genes: AGT APP CAPN1 CAPN2 CD93 CPN1 CTSG CTSK CTSL CTSS ECE1 ELANE F11 F2 FTL GP1BA HABP2 ITGB2 KLK1 KLKB1 KRT1 MEP1A PLAUR PLG PREP RXFP4 THBS1 VTN 60 interacting genes: ACTB AMOT ANXA2 APOH ATP5F1B C7 CDCP1 CHGA CLEC3B CP CPB2 CXCL2 CYFIP2 ENO1 EP300 F10 F2R F2RL1 F3 FN1 HMGB1 HRG HSPA1A HSPB1 HSPD1 IGF2 IGFBP3 KLK3 KNG1 LAMA1 LAMA3 MAPK14 MEP1A MMP3 MMP7 MMP9 NGF PAPPA PCOLCE PLAT PLAU PRDX4 PRNP RAP2A RBBP6 RUVBL1 S100A10 SERPINB13 SERPINB6 SERPINC1 SERPINE1 SERPINF2 SERPING1 SERPINI1 SMAD3 SMAD4 SPARC TFPI2 THBS1 YTHDC1
Entrez ID 3827 5340
HPRD ID 01970 01417
Ensembl ID ENSG00000113889 ENSG00000122194
Uniprot IDs P01042 P00747 Q5TEH5
PDB IDs 1NY2 2WOK 4ASQ 4ASR 4ECB 4ECC 5I25 6F27 6F3V 6F3W 6F3X 6F3Y 1B2I 1BML 1BUI 1CEA 1CEB 1DDJ 1HPJ 1HPK 1I5K 1KI0 1KRN 1L4D 1L4Z 1PK4 1PKR 1PMK 1QRZ 1RJX 2DOH 2DOI 2KNF 2L0S 2PK4 3UIR 4A5T 4CIK 4DCB 4DUR 4DUU 5HPG 5UGD 5UGG 6D3X 6D3Y 6D3Z 6D40 6OG4 6OQJ 6OQK 6Q1U
Enriched GO Terms of Interacting Partners?
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