KLRC2 and KLRD1

Data Source:
HPRD (in vivo)

		KLRC2	KLRD1
Description		killer cell lectin like receptor C2	killer cell lectin like receptor D1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Activating MHC Class Ib Receptor Activity Protein Antigen Binding	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding MHC Class Ib Protein Binding, Via Antigen Binding Groove Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Cellular Defense Response Signal Transduction Positive Regulation Of Natural Killer Cell Degranulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity	Negative Regulation Of T Cell Mediated Cytotoxicity Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Cell Surface Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		DAP12 interactions DAP12 signaling DAP12 signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling DAP12 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494)	Umami taste perception in obesity with metabolic syndrome ( 31005965)
Interacting Genes		3 interacting genes: FBP1 HLA-E KLRD1	6 interacting genes: HLA-B HLA-E HLA-G KLRC1 KLRC2 KLRC3
Entrez ID		3822	3824
HPRD ID		04202	04204
Ensembl ID		ENSG00000205809	ENSG00000134539
Uniprot IDs		P26717	Q13241 Q53ZY6
PDB IDs		2L35	1B6E 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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