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KLRD1

Description killer cell lectin like receptor D1
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GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Receptor Complex
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • MHC Class I Protein Complex Binding
  • MHC Class Ib Protein Binding, Via Antigen Binding Groove
  • Carbohydrate Binding
  • HLA-E Specific Inhibitory MHC Class Ib Receptor Activity
  • Protein Antigen Binding
Biological Process
  • Negative Regulation Of T Cell Mediated Cytotoxicity
  • Stimulatory C-type Lectin Receptor Signaling Pathway
  • Natural Killer Cell Mediated Immunity
  • Cell Surface Receptor Signaling Pathway
  • Innate Immune Response
  • Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
  • Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
  • Regulation Of Immune Response
Pathways
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • DAP12 interactions
  • DAP12 signaling
  • DAP12 signaling
Drugs
Diseases
GWAS
  • Umami taste perception in obesity with metabolic syndrome ( 31005965)
Interacting Genes 6 interacting genes: HLA-B HLA-E HLA-G KLRC1 KLRC2 KLRC3
Entrez ID 3824
HPRD ID 04204
Ensembl ID ENSG00000134539
Uniprot IDs Q13241 Q53ZY6
PDB IDs 1B6E 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025