KIF5A and KIF5C

Data Source:
HPRD (in vivo)

		KIF5A	KIF5C
Description		kinesin family member 5A	kinesin family member 5C
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Dendrite Cytoplasm Perikaryon Synapse Perinuclear Region Of Cytoplasm Axon Cytoplasm	Kinesin Complex Microtubule Dendrite Cytoplasm Ciliary Rootlet Neuronal Cell Body Axonal Growth Cone Distal Axon Axon Cytoplasm
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Chemical Synaptic Transmission Axon Guidance Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Retrograde Neuronal Dense Core Vesicle Transport	Organelle Organization Microtubule-based Movement Axon Guidance Motor Neuron Axon Guidance Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport MRNA Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport
Pathways		MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Insulin processing
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Amyotrophic lateral sclerosis ( 29566793) Rheumatoid arthritis ( 24449572 18794853) Smoking initiation (ever regular vs never regular) ( 30679032)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Chronotype ( 30696823)
Interacting Genes		18 interacting genes: DTNB ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 NDEL1 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TRIM55 TRIM63 TSG101 YAP1	8 interacting genes: CSNK2A1 KIF5A KLC1 KLC3 MEOX2 NCOA2 SNAPIN YWHAG
Entrez ID		3798	3800
HPRD ID		09108	18371
Ensembl ID		ENSG00000155980	ENSG00000168280
Uniprot IDs		Q12840	O60282 Q59GB8
PDB IDs		4UXT 4UXY 4UY0
Enriched GO Terms of Interacting Partners?
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