KCNK1 and CDIPT

Data Source:
BioGRID (two hybrid)

		KCNK1	CDIPT
Description		potassium two pore domain channel subfamily K member 1	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Apical Plasma Membrane Dendrite Brush Border Membrane Potassium Channel Complex Perikaryon Intracellular Membrane-bounded Organelle Recycling Endosome Synaptic Membrane Inward Rectifier Potassium Channel Complex	Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Sodium Channel Activity Protein Binding Potassium Ion Leak Channel Activity Identical Protein Binding	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding
	Biological Process	Potassium Ion Transport Stabilization Of Membrane Potential Response To Nicotine Sodium Ion Transmembrane Transport Regulation Of Resting Membrane Potential Cardiac Conduction Potassium Ion Transmembrane Transport	Phosphatidylinositol Biosynthetic Process
Pathways		Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential	Synthesis of PI
Drugs		Ibutilide Quinidine Quinidine barbiturate	scyllo-inositol
Diseases
GWAS		Cognitive function ( 28808816) Diabetic retinopathy ( 21441570) Periodontal microbiota ( 22699663) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Mean platelet volume ( 27863252)
Interacting Genes		13 interacting genes: AQP6 CDIPT CREB3 CREB3L1 ERGIC3 KRTAP10-3 LMNA SENP1 STOM TCIRG1 TMEM139 TMEM14B UBE2I	56 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SDCBP SIGLEC12 SLC10A6 SLC16A7 SLC7A1 TLCD4 TMX2 UNC93A VMA21
Entrez ID		3775	10423
HPRD ID		03447	12063
Ensembl ID		ENSG00000135750	ENSG00000103502
Uniprot IDs		A0A024R3T2 O00180	A8K3L7 B3KY94 O14735
PDB IDs		3UKM
Enriched GO Terms of Interacting Partners?
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