KCNK1

Description		potassium two pore domain channel subfamily K member 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Apical Plasma Membrane Dendrite Brush Border Membrane Potassium Channel Complex Perikaryon Intracellular Membrane-bounded Organelle Recycling Endosome Synaptic Membrane Inward Rectifier Potassium Channel Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Sodium Channel Activity Protein Binding Potassium Ion Leak Channel Activity Identical Protein Binding
	Biological Process	Potassium Ion Transport Stabilization Of Membrane Potential Response To Nicotine Sodium Ion Transmembrane Transport Regulation Of Resting Membrane Potential Cardiac Conduction Potassium Ion Transmembrane Transport
Pathways		Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential
Drugs		Ibutilide Quinidine Quinidine barbiturate
Diseases
GWAS		Cognitive function ( 28808816) Diabetic retinopathy ( 21441570) Periodontal microbiota ( 22699663) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		13 interacting genes: AQP6 CDIPT CREB3 CREB3L1 ERGIC3 KRTAP10-3 LMNA SENP1 STOM TCIRG1 TMEM139 TMEM14B UBE2I
Entrez ID		3775
HPRD ID		03447
Ensembl ID		ENSG00000135750
Uniprot IDs		A0A024R3T2 O00180
PDB IDs		3UKM
Enriched GO Terms of Interacting Partners?
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