KCNJ1 and APLP2

Data Source:
BioGRID (affinity chromatography technology)

		KCNJ1	APLP2
Description		potassium inwardly rectifying channel subfamily J member 1	amyloid beta precursor like protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome
	Molecular Function	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Potassium Ion Transport Excretion Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Platelet Degranulation G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Potassium transport channels	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Bethanidine Glimepiride Minoxidil Acetohexamide Tolbutamide Glymidine Yohimbine Agmatine Butamben	Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Bartter syndrome
GWAS			Blood protein levels ( 30072576)
Interacting Genes		6 interacting genes: GOLGA3 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2	23 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B
Entrez ID		3758	334
HPRD ID		08981	00103
Ensembl ID		ENSG00000151704	ENSG00000084234
Uniprot IDs		A0A024R3K6 A8K432 P48048	A0A140VJE9 B4E3I5 Q06481
PDB IDs			5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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