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SFT2D2 and INPP5K
Data Source:
BioGRID
(two hybrid)
SFT2D2
INPP5K
Description
SFT2 domain containing 2
inositol polyphosphate-5-phosphatase K
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Extracellular Exosome
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Molecular Function
Molecular_function
Protein Binding
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Biological Process
Biological_process
Protein Transport
Vesicle-mediated Transport
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phosphatidylinositol Biosynthetic Process
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transmembrane Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Pathways
Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS
Alzheimer's disease (
30636644
)
Mean platelet volume (
27863252
)
Interacting Genes
29 interacting genes:
AQP6
ATP5PF
BNIP2
CREB3
ELOVL4
GPR152
HIBADH
HSD17B11
HSD17B13
IFNGR2
INPP5K
LMNA
MOB2
NDRG4
PBX3
PLIN2
PLIN3
REEP2
REEP4
SLC10A1
SLC10A6
SLC30A8
STOM
TAS2R5
TCP11X2
TIMM44
TMEM143
TMEM14B
TMEM51
23 interacting genes:
ANXA7
ARL6IP1
ATP5PF
BDNF
CDKN1A
CPTP
FADS6
FATE1
FBXO7
GOLT1B
HMOX2
HSPB1
KRT31
MAD2L1BP
NCOR2
PBX3
PFDN1
SFT2D2
SMN1
TANK
TK1
TNFRSF10D
TTR
Entrez ID
375035
51763
HPRD ID
14192
08489
Ensembl ID
ENSG00000213064
ENSG00000132376
Uniprot IDs
O95562
B7Z4V9
Q9BT40
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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