NCR3LG1 and COL4A5

Data Source:
BioGRID (two hybrid)

		NCR3LG1	COL4A5
Description		natural killer cell cytotoxicity receptor 3 ligand 1	collagen type IV alpha 5 chain
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Collagen Type IV Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Regulation Of Immune Response	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs
Drugs
Diseases			Alport syndrome
GWAS		Body mass index ( 26426971) Circulating leptin levels or type 2 diabetes ( 32341051)
Interacting Genes		9 interacting genes: C14orf180 C3orf52 COL4A5 ERG28 PLPP6 STX8 TMEM14C TMEM222 TSPO	46 interacting genes: ABHD4 ANTXR2 ANXA7 APP ATP6V0B BSND CD53 CD79A CD93 CDKN1A CERS4 CLDN7 DAZAP2 DCN ELOVL4 ERGIC3 FAM209A FBLN2 FFAR2 FN1 GPX8 HABP2 KCNJ6 MATN2 MFF MMP9 MTIF3 NCR3LG1 NEMP1 NR1H2 OSM RELL2 RNF10 SAR1A SERPINE2 SLC10A4 SLC10A6 SLC16A2 SLC18A1 SLC35C2 SLC39A2 SMN1 THAP4 TK1 TMEM80 TSPO2
Entrez ID		374383	1287
HPRD ID		16820	02363
Ensembl ID		ENSG00000188211	ENSG00000188153
Uniprot IDs		Q68D85	A7MBN3 P29400 Q49AM6
PDB IDs		3PV6 3PV7 4ZSO 6YJP	5NAZ
Enriched GO Terms of Interacting Partners?
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