IL11 and MAGEA11

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		IL11	MAGEA11
Description		interleukin 11	MAGE family member A11
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Cytokine Activity Interleukin-11 Receptor Binding Protein Binding Growth Factor Activity	Protein Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Osteoarthritis (hip) ( 30374069) Response to antidepressants ( 20360315)
Interacting Genes		3 interacting genes: IL11RA MAGEA11 UBQLN2	114 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC105 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEX37 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		3589	4110
HPRD ID		00980	02281
Ensembl ID		ENSG00000095752	ENSG00000185247
Uniprot IDs		A8K3F7 P20809	G5E962 P43364
PDB IDs		4MHL 6O4O	6WJH
Enriched GO Terms of Interacting Partners?
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