KRTAP12-1 and PEF1

Data Source:
BioGRID (two hybrid)

		KRTAP12-1	PEF1
Description		keratin associated protein 12-1	penta-EF-hand domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Keratinization	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways		Keratinization
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		60 interacting genes: CATSPER1 CHRD CYSRT1 DHRS1 ENKD1 FHL3 GATA3 GPRIN2 GRN HOXA1 HOXC8 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C MEOX2 MGAT5B NBPF19 NEU4 NOTCH2NLA OTX1 PDIA2 PDIA4 PEF1 POU2AF1 POU4F2 PRR35 RBPMS SMCP TOX TRIP13 UBQLN2 VGLL3 ZIC1	40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 C11orf1 CALCOCO2 CEP55 CTAG1A CTAG1B CUL3 DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KLHL12 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG VPS37C WWOX ZIC1
Entrez ID		353332	553115
HPRD ID		11197	10143
Ensembl ID		ENSG00000187175	ENSG00000162517
Uniprot IDs		P59990	A0A384MQX5 Q9UBV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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