PEF1 and HYDIN

Data Source:
BioGRID (two hybrid)

		PEF1	HYDIN
Description		penta-EF-hand domain containing 1	HYDIN axonemal central pair apparatus protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Axonemal Central Apparatus Axonemal Central Pair Projection
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Epithelial Cell Development Cilium Movement Ventricular System Development Trachea Development Axonemal Central Apparatus Assembly
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)	Apolipoprotein B levels ( 32203549) Celiac disease ( 23936387) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Coffee consumption ( 31046077) Diastolic blood pressure ( 30578418) Hematocrit ( 27863252) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Malaria ( 31844061) Pulse pressure ( 30578418)
Interacting Genes		40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 C11orf1 CALCOCO2 CEP55 CTAG1A CTAG1B CUL3 DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KLHL12 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG VPS37C WWOX ZIC1	3 interacting genes: ERRFI1 PEF1 UBC
Entrez ID		553115	54768
HPRD ID		10143	11042
Ensembl ID		ENSG00000162517	ENSG00000157423
Uniprot IDs		A0A384MQX5 Q9UBV8	Q4G0P3
PDB IDs			2E6J 2YS4
Enriched GO Terms of Interacting Partners?
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