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LCE1F and FBLN1
Data Source:
BioGRID
(two hybrid)
LCE1F
FBLN1
Description
late cornified envelope 1F
fibulin 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Matrix
Collagen-containing Extracellular Matrix
Extracellular Exosome
Elastic Fiber
Molecular Function
Protein Binding
Identical Protein Binding
Fibronectin Binding
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein C-terminus Binding
Peptidase Activator Activity
Identical Protein Binding
Protein-containing Complex Binding
Fibrinogen Binding
Biological Process
Keratinization
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cell Adhesion
Integrin-mediated Signaling Pathway
Positive Regulation Of Peptidase Activity
Viral Process
Extracellular Matrix Organization
Negative Regulation Of ERK1 And ERK2 Cascade
Blood Coagulation, Fibrin Clot Formation
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Cell Motility
Negative Regulation Of Stem Cell Proliferation
Pathways
Formation of the cornified envelope
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Drugs
Diseases
Synpolydactyly, 3/3'4, associated with metacarpal and metatarsal synostoses
GWAS
Asthma (
31619474
)
Blood protein levels (
30072576
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Low density lipoprotein cholesterol levels (
32154731
)
Paneth cell defects in Crohn's disease (
28352666
)
QT interval (
29213071
)
Red blood cell count (
27863252
)
Temperament (bipolar disorder) (
22365631
)
Interacting Genes
74 interacting genes:
ADAMTSL4
ALPP
CATSPER1
CHIC2
CHRD
CRCT1
CYP21A2
CYSRT1
FBLN1
HOXA1
IL34
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-10
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP2-3
KRTAP2-4
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE2B
LCE2C
LCE2D
LCE3B
LCE5A
MACO1
MDFI
NBPF19
NOTCH2NLA
NTAQ1
OIT3
OTX1
PCSK5
POU4F2
PSMB1
RAD54L2
RGS20
RNF4
SLC39A7
SMCP
SPRY1
SPRY2
SPRY3
TRIM42
UBE2I
VWC2
WFDC3
62 interacting genes:
ACAN
ADAMTSL2
ADAMTSL4
AK3
ALG10
APOA1
APP
ATN1
BHLHE40
CACNA1A
CCN2
CCN3
CHIC2
CREB5
CXCL5
DDIAS
ECM1
EDC4
ELN
FGB
FN1
GFI1B
HBEGF
HOXA1
HSPG2
ITGB1
KRTAP11-1
KRTAP19-2
LCE1A
LCE1B
LCE1C
LCE1F
LCE3A
LCE5A
LINGO1
LMNTD2
LTBP4
MCPH1
MEOX2
MFAP5
MOB4
MRPL12
NEDD1
NID1
NLGN3
NOTCH3
PAX5
PLSCR1
PPARA
SKIL
SLC66A2
SMAD3
SMAD4
SPRY1
TAF9
TANK
TCF7L2
TDGF1
TRIM42
UNKL
VCAN
YWHAQ
Entrez ID
353137
2192
HPRD ID
13970
00629
Ensembl ID
ENSG00000240386
ENSG00000077942
Uniprot IDs
Q5T754
P23142
Q8NBH6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
?
Tagcloud (Intersection)
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