LCE1E and RGS17

Data Source:
BioGRID (two hybrid)

		LCE1E	RGS17
Description		late cornified envelope 1E	regulator of G protein signaling 17
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Keratinization	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Formation of the cornified envelope	G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Asthma ( 31619474) Inflammatory skin disease ( 25574825)	Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549)
Interacting Genes		59 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2B LCE2C LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NOTCH2NLA NTAQ1 PIAS2 RGS17 RNF4 SMCP TGM1 TRIM42 ZCCHC7	43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN
Entrez ID		353135	26575
HPRD ID		13969	06223
Ensembl ID		ENSG00000186226	ENSG00000091844
Uniprot IDs		Q5T753	Q9UGC6
PDB IDs			1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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