RGS17 and LCE3D

Data Source:
BioGRID (two hybrid)

		RGS17	LCE3D
Description		regulator of G protein signaling 17	late cornified envelope 3D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse	Cytosol
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Cornification
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	Formation of the cornified envelope
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Psoriasis ( 25854761 20953190 23143594 19169255)
Interacting Genes		43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN	55 interacting genes: ADAMTSL4 ALPP CCN3 CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-5 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2B LCE2C MDFI NBPF19 NOTCH2NLA PCSK5 RGS17 RGS20 SDC3 SPRY1 SPRY3 SRPK1 SRPK2 TENM4 TGFB1 TRIM42 TSPAN4 VWC2
Entrez ID		26575	84648
HPRD ID		06223	17263
Ensembl ID		ENSG00000091844	ENSG00000163202
Uniprot IDs		Q9UGC6	Q9BYE3
PDB IDs		1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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