IGF1R and VAV3

  • Data Source:
  • HPRD (in vivo)

IGF1R

VAV3

Description insulin like growth factor 1 receptor vav guanine nucleotide exchange factor 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Asthma and hay fever ( 24388013)
  • Autoimmune thyroid disease ( 32581359)
  • Bipolar disorder ( 31043756)
  • Differentiated thyroid cancer ( 28703219)
  • Eosinophil percentage of white cells ( 32888494)
  • Hashimoto thyroiditis versus Graves' disease ( 25429627)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hypothyroidism ( 30367059 27182965 22493691)
  • IgA nephropathy ( 25305756)
  • Medication use (thyroid preparations) ( 31015401)
  • Night sleep phenotypes ( 27126917)
  • Papillary thyroid cancer ( 28703219)
  • Plasma thyroid-stimulating hormone levels ( 24722205)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Thyroid stimulating hormone levels ( 32769997)
Interacting Genes 95 interacting genes: AMY2A APP ARHGEF12 BAP1 CAV1 CBL CDK4 CDKN2B CRK CRKL CSK CYP17A1 DOK4 DOK5 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 EEA1 EHD1 ERBB2 ESR1 FFAR2 FGFR4 GIPC1 GNAI1 GNAI2 GRB10 GRB14 GRM1 HOXC6 IGF1 IGF2 IGFBP3 IL13RA2 ILKAP INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KDELR2 KL KLK5 KRT27 LYPD3 MAP3K5 MDM2 MTA3 NAT2 NEDD4 NF2 PCNA PIK3R1 PIK3R2 PIK3R3 PPM1A PRKCD PRKD1 PTPN1 PTPN11 PTPN12 PTPN6 PTPN7 PTPRR RACK1 RASA1 RELA RPL11 SH2B1 SHC1 SIRPA SOCS1 SOCS2 SOCS3 SRC STAT3 STYX THRSP TTYH2 UBC VAV3 VPS45 YWHAB YWHAE YWHAG YWHAZ 25 interacting genes: AR CBLB EGFR ERBB2 ERBB3 ERBB4 ESR1 GAB1 GRB2 IGF1R INSR KIT LCP2 MET PIK3R1 PLCG1 RAC1 RHOA RHOG RINT1 ROS1 SH3BP2 SHC1 ZRANB1 ZYX
Entrez ID 3480 10451
HPRD ID 00932 05706
Ensembl ID ENSG00000140443 ENSG00000134215
Uniprot IDs C9J5X1 P08069 Q9UKW4
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 4D2R 4XSS 5FXQ 5FXR 5FXS 5HZN 5U8Q 5U8R 6JK8 6VWG 6VWH 6VWI 6VWJ 2D86
Enriched GO Terms of Interacting Partners?
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