MSL1 and FCHSD2

Data Source:
BioGRID (two hybrid)

		MSL1	FCHSD2
Description		MSL complex subunit 1	FCH and double SH3 domains 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck MSL Complex	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Histone H4-K16 Acetylation	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Asthma ( 31619474)	Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)
Interacting Genes		17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		339287	9873
HPRD ID		19425	13321
Ensembl ID		ENSG00000188895	ENSG00000137478
Uniprot IDs		B3KWR7 Q68DK7	O94868
PDB IDs		4B7Y 4B86 4DNC	2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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