APLP1 and HSPE1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	HSPE1
Description		amyloid beta precursor like protein 1	heat shock protein family E (Hsp10) member 1
Image
GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Phenethyl Isothiocyanate
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	16 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 NTAQ1 SAT1 SELENOM STK3 TLE1 UNC119 ZHX1
Entrez ID		333	3336
HPRD ID		00102	02535
Ensembl ID		ENSG00000105290	ENSG00000115541
Uniprot IDs		P51693	A0A384N6A4 P61604
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA	4PJ1 6HT7 6MRC 6MRD
Enriched GO Terms of Interacting Partners?
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