APLP1 and GSTM4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	GSTM4
Description		amyloid beta precursor like protein 1	glutathione S-transferase mu 4
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GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process Glutathione Derivative Biosynthetic Process
Pathways			Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Seasonality and depression ( 30217971)
Interacting Genes		43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	11 interacting genes: APLP1 GSTM3 GSTM5 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		333	2948
HPRD ID		00102	00706
Ensembl ID		ENSG00000105290	ENSG00000168765
Uniprot IDs		P51693	A0A140VKE3 Q03013
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA	4GTU
Enriched GO Terms of Interacting Partners?
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