HSBP1 and CD1B

Data Source:
HPRD (in vitro, in vivo)

		HSBP1	CD1B
Description		heat shock factor binding protein 1	CD1b molecule
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton	Extracellular Space Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Immune Response
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25	2 interacting genes: B2M PSAP
Entrez ID		3281	910
HPRD ID		05185	01775
Ensembl ID		ENSG00000230989	ENSG00000158485
Uniprot IDs		O75506	P29016
PDB IDs		3CI9	1GZP 1GZQ 1UQS 2H26 3OV6 3T8X 4ONO 5C9J 5L2J 5L2K 5WKE 5WKG 5WKI 5WL1 6CUG 6D64
Enriched GO Terms of Interacting Partners?
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