HOXD4 and ASB8

Data Source:
BioGRID (two hybrid)

		HOXD4	ASB8
Description		homeobox D4	ankyrin repeat and SOCS box containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cell Junction	Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		21 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 FANCL HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 PBX4 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	6 interacting genes: ELOB HOXD4 MCM7 RCN1 RIN3 SERTAD1
Entrez ID		3233	140461
HPRD ID		00864	10675
Ensembl ID		ENSG00000170166	ENSG00000177981
Uniprot IDs		P09016	F5GYF0 Q9H765
PDB IDs
Enriched GO Terms of Interacting Partners?
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