HOXB2 and MNDA

Data Source:
HPRD (in vitro)

		HOXB2	MNDA
Description		homeobox B2	myeloid cell nuclear differentiation antigen
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Extracellular Region Nucleoplasm Nucleolus Cytosol Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Double-stranded DNA Binding Protein Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Blood Circulation Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 3 Development Rhombomere 4 Development Facial Nerve Structural Organization Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Neural Nucleus Development	Activation Of Innate Immune Response Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Positive Regulation Of Apoptotic Process Neutrophil Degranulation B Cell Receptor Signaling Pathway
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Experiencing mood swings ( 29500382) Feeling hurt ( 29500382) Primary tooth development (number of teeth) ( 20195514)	Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Perceived intensity of aspartame ( 31005972)
Interacting Genes		13 interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410	13 interacting genes: CDK1 CDK2 CRK FBXO7 HOXB2 MAPK8IP2 NSD3 PRMT6 PRMT7 RB1 RBL2 STAT3 TP53
Entrez ID		3212	4332
HPRD ID		00854	15932
Ensembl ID		ENSG00000173917	ENSG00000163563
Uniprot IDs		P14652	P41218 Q5VUU6
PDB IDs			2DBG 5H7Q 5WPZ
Enriched GO Terms of Interacting Partners?
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