HNRNPAB and DBN1

Data Source:
BioGRID (proximity labelling technology)

		HNRNPAB	DBN1
Description		heterogeneous nuclear ribonucleoprotein A/B	drebrin 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		19 interacting genes: ACTB CDC42 DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG	27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598
Entrez ID		3182	1627
HPRD ID		04067	00545
Ensembl ID		ENSG00000197451	ENSG00000113758
Uniprot IDs		Q99729	Q16643
PDB IDs		3S7R	5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?
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