AOX1 and BCS1L

Data Source:
BioGRID (two hybrid)

		AOX1	BCS1L
Description		aldehyde oxidase 1	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane
	Molecular Function	Aldehyde Oxidase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity Identical Protein Binding Protein Homodimerization Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding NAD Binding 2 Iron, 2 Sulfur Cluster Binding FAD Binding Geranial:oxygen Oxidoreductase Activity Heptaldehyde:oxygen Oxidoreductase Activity	Protein Binding ATP Binding ATPase Activity
	Biological Process	Drug Metabolic Process Electron Transport Chain Vitamin B6 Metabolic Process	Mitochondrion Organization Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Cytochrome C Oxidase Assembly Mitochondrial Respiratory Chain Complex III Assembly
Pathways		Vitamins B6 activation to pyridoxal phosphate	Mitochondrial protein import
Drugs		Cyclobenzaprine Eniluracil
Diseases		Xanthinuria	Bjornstad syndrome Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Hip circumference adjusted for BMI ( 28552196) Intelligence ( 22449649) Late-onset Alzheimer's disease ( 27770636)	Male-pattern baldness ( 28196072)
Interacting Genes		6 interacting genes: ABCA1 CRKL ERRFI1 GK RBL1 RCHY1	3 interacting genes: DDX24 DNAJA1 MTDH
Entrez ID		316	617
HPRD ID		07537	04708
Ensembl ID		ENSG00000138356	ENSG00000074582
Uniprot IDs		Q06278	A0A024R445 A8JZZ8 Q9Y276
PDB IDs		4UHW 4UHX 5EPG 6Q6Q
Enriched GO Terms of Interacting Partners?
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