GK and OPLAH

Data Source:
BioGRID (two hybrid)

		GK	OPLAH
Description		glycerol kinase	5-oxoprolinase, ATP-hydrolysing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Extracellular Exosome	Cytosol
	Molecular Function	Glycerol Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor	Protein Binding ATP Binding 5-oxoprolinase (ATP-hydrolyzing) Activity Identical Protein Binding
	Biological Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glycerol-3-phosphate Biosynthetic Process	Glutathione Metabolic Process Glutathione Biosynthetic Process
Pathways		Triglyceride biosynthesis	Glutathione synthesis and recycling Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Drugs			Glutamic acid
Diseases		Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
GWAS		Cardiovascular risk factors (age interaction) ( 20838585)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Blood metabolite levels ( 24816252) Mean spheric corpuscular volume ( 32888494) Metabolic traits ( 21886157) Serum metabolite levels ( 23093944)
Interacting Genes		11 interacting genes: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA	4 interacting genes: GK POU6F2 TPK1 ZNF451
Entrez ID		2710	26873
HPRD ID		08363	14880
Ensembl ID		ENSG00000198814	ENSG00000178814
Uniprot IDs		B4DH54 P32189	O14841
PDB IDs
Enriched GO Terms of Interacting Partners?
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