TAX1BP3 and CDK5RAP3

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		TAX1BP3	CDK5RAP3
Description		Tax1 binding protein 3	CDK5 regulatory subunit associated protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleolus Cytoplasm Centrosome Cytosol Microtubule Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Beta-catenin Binding Protein C-terminus Binding	Protein Binding Protein Kinase Binding Cyclin Binding Ubiquitin-like Protein Ligase Binding Mitogen-activated Protein Kinase Binding NF-kappaB Binding MDM2/MDM4 Family Protein Binding
	Biological Process	Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Activation Of GTPase Activity Negative Regulation Of Protein Localization To Cell Surface	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Liver Development Negative Regulation Of Protein Phosphorylation Mitotic G2 DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Brain Development Cell Population Proliferation Regulation Of Phosphatase Activity Viral Process Apoptotic Nuclear Changes Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Endoplasmic Reticulum Stress Negative Regulation Of MAP Kinase Activity Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Mitotic G2/M Transition Checkpoint Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Definitive Erythrocyte Differentiation Protein Ufmylation Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 26426971) Generalized epilepsy ( 22949513) Metabolite levels (Pyroglutamine) ( 23934736)
Interacting Genes		13 interacting genes: ARNT2 CDK5RAP3 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29	13 interacting genes: CDK5R1 CREBBP CRMP1 DISC1 ESS2 FKBP6 HSPB1 KPNA2 SRPRB TAB1 TAX1BP3 TSPYL4 UFL1
Entrez ID		30851	80279
HPRD ID		18160	12190
Ensembl ID		ENSG00000213977	ENSG00000108465
Uniprot IDs		A0A087X282 O14907	Q96JB5
PDB IDs		2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B 4NNL 4NNM
Enriched GO Terms of Interacting Partners?
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