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HCRT and NPFFR2
Data Source:
HPRD
(in vivo)
HCRT
NPFFR2
Description
hypocretin neuropeptide precursor
neuropeptide FF receptor 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Rough Endoplasmic Reticulum
Synaptic Vesicle
Secretory Granule
Perinuclear Region Of Cytoplasm
Postsynapse
Plasma Membrane
Integral Component Of Plasma Membrane
Actin Cytoskeleton
Molecular Function
Neuropeptide Hormone Activity
Type 1 Hypocretin Receptor Binding
Type 2 Hypocretin Receptor Binding
G Protein-coupled Receptor Activity
Neuropeptide Receptor Activity
Opioid Receptor Binding
Peptide Binding
Biological Process
Temperature Homeostasis
G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Chemical Synaptic Transmission
Negative Regulation Of DNA Replication
Sleep
Response To Starvation
Eating Behavior
Negative Regulation Of Potassium Ion Transport
Regulation Of Neurotransmitter Secretion
Positive Regulation Of Calcium Ion Transport
Negative Regulation Of Transmission Of Nerve Impulse
Positive Regulation Of Transmission Of Nerve Impulse
Excitatory Postsynaptic Potential
Positive Regulation Of Cold-induced Thermogenesis
G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Detection Of Abiotic Stimulus
Regulation Of MAPK Cascade
Regulation Of Adenylate Cyclase Activity
Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events
Drugs
Pidolic acid
Diseases
GWAS
Interacting Genes
3 interacting genes:
HCRTR1
HCRTR2
NPFFR2
6 interacting genes:
FKBP7
HCRT
NPFF
NPY
TMEM218
TRARG1
Entrez ID
3060
10886
HPRD ID
03836
16244
Ensembl ID
ENSG00000161610
ENSG00000056291
Uniprot IDs
O43612
A0PJM9
Q9Y5X5
PDB IDs
1CQ0
1R02
1UVQ
1WSO
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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