HBZ and KHDRBS3

Data Source:
BioGRID (two hybrid)

		HBZ	KHDRBS3
Description		hemoglobin subunit zeta	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin ( 32888494) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 29403010 32888494)	Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		29 interacting genes: APP CARD10 CCNDBP1 CYSRT1 DOCK8 FGFR3 GOLGA6L9 HBB HBD HBE1 HBM HBQ1 HNRNPD HNRNPK IKBKG KHDRBS2 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MTUS2 NBPF19 NOTCH2NLA NTAQ1 RBMY1A1 SP1 UPF2	54 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688
Entrez ID		3050	10656
HPRD ID		00794	10007
Ensembl ID		ENSG00000130656	ENSG00000131773
Uniprot IDs		P02008	O75525
PDB IDs		1JEB 3W4U	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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