ERO1A and KLHDC2

Data Source:
BioGRID (affinity chromatography technology)

		ERO1A	KLHDC2
Description		endoplasmic reticulum oxidoreductase 1 alpha	kelch domain containing 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle	Nucleoplasm Nuclear Body Nuclear Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor	Protein Binding
	Biological Process	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Protein Phosphopantetheinylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		12 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 LHX4 LINC01554 P4HB PDIA3 PDILT PELI2 RHOU	5 interacting genes: EZH2 SELENOK SELENOS STRN4 USP1
Entrez ID		30001	23588
HPRD ID		13278	08824
Ensembl ID		ENSG00000197930	ENSG00000165516
Uniprot IDs		Q96HE7	Q9Y2U9
PDB IDs		3AHQ 3AHR	6DO3 6DO4 6DO5
Enriched GO Terms of Interacting Partners?
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