PKN3 and ARHGAP26

Data Source:
HPRD (in vivo, two hybrid)

		PKN3	ARHGAP26
Description		protein kinase N3	Rho GTPase activating protein 26
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Perinuclear Region Of Cytoplasm	Cellular_component Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding	GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process	Protein Phosphorylation Signal Transduction Epithelial Cell Migration Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Signal Transduction Nervous System Development Actin Cytoskeleton Organization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHO GTPases activate PKNs	Rho GTPase cycle
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Asthma ( 31361310) Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457) Gamma glutamyl transferase levels ( 29403010) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) White blood cell count ( 32888494)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Pulse pressure ( 27841878) Waist circumference ( 28552196)
Interacting Genes		9 interacting genes: ARHGAP10 ARHGAP26 GOLGA2 KRT31 MTUS2 PLD1 PNMA1 TFIP11 VPS52	8 interacting genes: CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1
Entrez ID		29941	23092
HPRD ID		17856	05643
Ensembl ID		ENSG00000160447	ENSG00000145819
Uniprot IDs		A0A024R8D6 Q6P5Z2	A0A0S2Z536 Q9UNA1
PDB IDs			1UGV
Enriched GO Terms of Interacting Partners?
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