DSE and ACSL4

Data Source:
BioGRID (two hybrid)

		DSE	ACSL4
Description		dermatan sulfate epimerase	acyl-CoA synthetase long chain family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Cytoplasm Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Membrane Integral Component Of Membrane Neuronal Cell Body Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	Chondroitin-glucuronate 5-epimerase Activity	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity
	Biological Process	Heparan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Metabolic Process Dermatan Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Dermatan Sulfate Biosynthetic Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Response To Nutrient Fatty Acid Transport Triglyceride Biosynthetic Process Neuron Differentiation Positive Regulation Of Insulin Secretion Long-chain Fatty-acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Embryonic Process Involved In Female Pregnancy Dendritic Spine Development Response To Interleukin-15
Pathways		Dermatan sulfate biosynthesis	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs
Drugs			Icosapent Troglitazone Rosiglitazone
Diseases			Non-syndromic X-linked mental retardation
GWAS		Depressive symptoms x dependent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Fast beta electroencephalogram ( 28040410) Height ( 28552196) Heschl's gyrus morphology ( 25130324) Mean platelet volume ( 32888494) Platelet count ( 32888494) Refractive error ( 32231278) Systemic lupus erythematosus ( 33536424)	Mean platelet volume ( 32888494)
Interacting Genes		2 interacting genes: ACSL4 INTS11	4 interacting genes: APP DSE HTATIP2 YWHAQ
Entrez ID		29940	2182
HPRD ID		05807	02152
Ensembl ID		ENSG00000111817	ENSG00000068366
Uniprot IDs		A0A2R8YE23 A0A2U3TZJ0 B7Z1T3 B7Z765 Q9UL01	O60488 Q8TAF6
PDB IDs		6HZN
Enriched GO Terms of Interacting Partners?
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