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ACSL4

Description acyl-CoA synthetase long chain family member 4
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrial Outer Membrane
  • Peroxisomal Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Plasma Membrane
  • Membrane
  • Integral Component Of Membrane
  • Neuronal Cell Body
  • Mitochondria-associated Endoplasmic Reticulum Membrane
  • Extracellular Exosome
Molecular Function
  • Long-chain Fatty Acid-CoA Ligase Activity
  • ATP Binding
  • Very Long-chain Fatty Acid-CoA Ligase Activity
  • Arachidonate-CoA Ligase Activity
Biological Process
  • Long-chain Fatty Acid Metabolic Process
  • Lipid Metabolic Process
  • Response To Nutrient
  • Fatty Acid Transport
  • Triglyceride Biosynthetic Process
  • Neuron Differentiation
  • Positive Regulation Of Insulin Secretion
  • Long-chain Fatty-acyl-CoA Metabolic Process
  • Long-chain Fatty-acyl-CoA Biosynthetic Process
  • Embryonic Process Involved In Female Pregnancy
  • Dendritic Spine Development
  • Response To Interleukin-15
Pathways
  • Intracellular metabolism of fatty acids regulates insulin secretion
  • Synthesis of very long-chain fatty acyl-CoAs
Drugs
  • Icosapent
  • Troglitazone
  • Rosiglitazone
Diseases
  • Non-syndromic X-linked mental retardation
GWAS
  • Mean platelet volume ( 32888494)
Interacting Genes 4 interacting genes: APP DSE HTATIP2 YWHAQ
Entrez ID 2182
HPRD ID 02152
Ensembl ID ENSG00000068366
Uniprot IDs O60488 Q8TAF6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025