SEC61A1 and ACAD9

Data Source:
BioGRID (affinity chromatography technology)

		SEC61A1	ACAD9
Description		SEC61 translocon subunit alpha 1	acyl-CoA dehydrogenase family member 9
Image			No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane Dendrite Mitochondrial Membrane
	Molecular Function	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport	Long-chain Fatty Acid Metabolic Process Mitochondrial Respiratory Chain Complex I Assembly Medium-chain Fatty Acid Metabolic Process
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane	Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)	Dental caries ( 23064961) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes		10 interacting genes: BAG6 CALM1 GET3 HSPA5 MLH1 PTEN SEC61G SERP1 SLC13A1 TNF
Entrez ID		29927	28976
HPRD ID		15316	12412
Ensembl ID		ENSG00000058262	ENSG00000177646
Uniprot IDs		B3KME8 B3KNF6 P61619	Q9H845
PDB IDs		6W6L
Enriched GO Terms of Interacting Partners?
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