SEC61A1 and SEC61G

Data Source:
BioGRID (pull down)

		SEC61A1	SEC61G
Description		SEC61 translocon subunit alpha 1	SEC61 translocon subunit gamma
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GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Ssh1 Translocon Complex
	Molecular Function	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding	Protein Binding Protein Transmembrane Transporter Activity P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport	Posttranslational Protein Targeting To Membrane, Translocation Protein Targeting To ER
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane	ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)	Metabolite levels ( 23823483) Systemic lupus erythematosus ( 24871463) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		10 interacting genes: BAG6 CALM1 GET3 HSPA5 MLH1 PTEN SEC61G SERP1 SLC13A1 TNF	10 interacting genes: AQP6 CREB3 CREB3L1 FAM209A LCN2 LRRC25 PEX12 SEC61A1 SFTPC TMEM51
Entrez ID		29927	23480
HPRD ID		15316	15318
Ensembl ID		ENSG00000058262	ENSG00000132432
Uniprot IDs		B3KME8 B3KNF6 P61619	A0A024QYZ0 P60059
PDB IDs		6W6L	6W6L
Enriched GO Terms of Interacting Partners?
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