STRN4 and ASNS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STRN4	ASNS
Description		striatin 4	asparagine synthetase (glutamine-hydrolyzing)
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Dendrite Dendritic Spine FAR/SIN/STRIPAK Complex	Cytosol
	Molecular Function	Protein Binding Calmodulin Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding	Asparagine Synthase (glutamine-hydrolyzing) Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Biological_process	Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus PERK-mediated Unfolded Protein Response Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress Aspartate and asparagine metabolism Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs			Aspartic acid Glutamic acid ATP Asparagine
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)	Regular attendance at a religious group ( 29970889) Tuberculosis ( 30713548)
Interacting Genes		23 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 WIPI2 WNT7A	5 interacting genes: ATXN1 STRN4 SUMO2 TRIM69 WDR27
Entrez ID		29888	440
HPRD ID		18125	00153
Ensembl ID		ENSG00000090372	ENSG00000070669
Uniprot IDs		B3KPF6 Q59GV6 Q9NRL3	P08243
PDB IDs			6GQ3
Enriched GO Terms of Interacting Partners?
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