ZDHHC8 and RTN4R

Data Source:
BioGRID (affinity chromatography technology)

		ZDHHC8	RTN4R
Description		zinc finger DHHC-type palmitoyltransferase 8	reticulon 4 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Integral Component Of Membrane Mitochondrial Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Anchored Component Of External Side Of Plasma Membrane Neuron Projection Neuronal Cell Body Dendritic Shaft Perikaryon Axonal Growth Cone Membrane Raft Extracellular Exosome
	Molecular Function	Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Protein Binding Heparin Binding Chondroitin Sulfate Binding Signaling Receptor Activity Neuregulin Receptor Activity Ganglioside GM1 Binding Ganglioside GT1b Binding
	Biological Process	Locomotory Behavior Positive Regulation Of Cholesterol Efflux Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation High-density Lipoprotein Particle Assembly Positive Regulation Of Protein Localization To Plasma Membrane	Cell Surface Receptor Signaling Pathway Negative Regulation Of Neuron Projection Development Corpus Callosum Development Neuronal Signal Transduction Negative Regulation Of Axon Extension Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of Axon Regeneration Negative Regulation Of Axonogenesis
Pathways		HDL assembly	Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Obesity-related traits ( 23251661)
Interacting Genes			9 interacting genes: HOXA1 LINGO1 MAG MGAT5B NGFR OMG OTX1 RTN4 RTN4IP1
Entrez ID		29801	65078
HPRD ID		12298	16123
Ensembl ID		ENSG00000099904	ENSG00000040608
Uniprot IDs		Q9ULC8	Q9BZR6
PDB IDs			1OZN 1P8T
Enriched GO Terms of Interacting Partners?
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