METTL17 and SF3B4

Data Source:
BioGRID (two hybrid)

		METTL17	SF3B4
Description		methyltransferase like 17	splicing factor 3b subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosyl-L-methionine Binding	RNA Binding Protein Binding Splicing Factor Binding
	Biological Process	Translation Methylation Ribosomal Small Subunit Biogenesis	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Degraded stimulus continuous performance test score ( 31596458)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth length ( 25281659) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 20881960 31562340 18391951) Infant length ( 25281659) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		21 interacting genes: ATXN1 ATXN1L CALCOCO2 CARD10 CBY2 CEP70 KRT34 KRT40 MAPK6 MDFI MEOX2 MID2 MTUS2 NUDT16L1 NUTM1 PNMA1 SF3B4 TFIP11 TRAF1 TRIP6 VCP	104 interacting genes: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-3 MIR9-1 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NCK2 NUB1 PPP1R16B PRPF40A QARS1 RAMAC RBM10 RBM39 RBM4 RPP25 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 TFG TLE5 TRAF4 U2AF2 UBASH3A WBP4 WDR77 ZCCHC10 ZNF3 ZNF48
Entrez ID		64745	10262
HPRD ID		13379	12028
Ensembl ID		ENSG00000165792	ENSG00000143368
Uniprot IDs		A0A0S2Z5L8 Q9H7H0	B3KUJ0 Q15427
PDB IDs			1X5T 5GVQ 5Z56 5Z57 5Z58 6AH0 6QX9 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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