GSTM2 and GSTM5

Data Source:
BioGRID (two hybrid)

		GSTM2	GSTM5
Description		glutathione S-transferase mu 2	glutathione S-transferase mu 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Sarcoplasmic Reticulum Intercellular Bridge Extracellular Exosome	Cytosol Intercellular Bridge
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Signaling Receptor Binding Fatty Acid Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding	Glutathione Transferase Activity Protein Binding Identical Protein Binding
	Biological Process	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Linoleic Acid Metabolic Process Hepoxilin Biosynthetic Process Relaxation Of Cardiac Muscle Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Detoxification Of Nitrogen Compound Cellular Response To Caffeine Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Glutathione Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Glutathione conjugation	Glutathione conjugation
Drugs		Glutathione S-(2,4-dinitrophenyl)glutathione Glutathione disulfide Glutathione disulfide S-Methyl glutathione	Glutathione Glutathione disulfide
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Metabolite levels ( 31628463) Urinary metabolite levels in chronic kidney disease ( 31959995)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		4 interacting genes: GSTM1 GSTM3 GSTM5 PTEN	6 interacting genes: AMOTL2 CDC42 GPKOW GSTM2 GSTM3 GSTM4
Entrez ID		2946	2949
HPRD ID		00710	00711
Ensembl ID		ENSG00000213366	ENSG00000134201
Uniprot IDs		A0A384P5E9 P28161 Q0D2I8	P46439 Q5T8R2
PDB IDs		1HNA 1HNB 1HNC 1XW5 1YKC 2AB6 2C4J 2GTU 3GTU 3GUR 5HWL
Enriched GO Terms of Interacting Partners?
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