GSTM5 and AMOTL2

Data Source:
BioGRID (two hybrid)

		GSTM5	AMOTL2
Description		glutathione S-transferase mu 5	angiomotin like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intercellular Bridge	Cytosol Plasma Membrane Bicellular Tight Junction Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Glutathione Transferase Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Glutathione Metabolic Process Glutathione Derivative Biosynthetic Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling
Pathways		Glutathione conjugation	Signaling by Hippo
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)	Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		6 interacting genes: AMOTL2 CDC42 GPKOW GSTM2 GSTM3 GSTM4	91 interacting genes: AMOT BFSP2 BLZF1 BRMS1L BYSL CARD9 CCDC185 CCDC196 CCDC57 CCHCR1 CDC37 CDR2 CHCHD3 CINP CYTH4 DAXX DDIT3 DTNB DYNLL1 DZIP1L EIF4E2 FAM184A FAM90A1 FBXO7 FCRL5 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KIF9 KRT1 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 L3MBTL2 LMNB2 LMO3 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MORF4L2 MPP1 MTMR6 MTNR1A MYO5B NDC80 NF2 NFIL3 NME7 NTAQ1 PIBF1 PPP2CA PPP2R1A PRKAA2 PRPF18 PSMC3 RAD51D RALBP1 RASAL3 RASSF5 RNF20 RNF40 RNF8 SAAL1 SH3RF2 SMARCE1 SOGA1 SP100 SPAG5 SPOP SPP1 TCEA2 THRA TMCC2 TNKS2 TRAF2 TRIM27 TSGA10IP YES1 ZBED1 ZBTB16 ZGPAT
Entrez ID		2949	51421
HPRD ID		00711	16485
Ensembl ID		ENSG00000134201	ENSG00000114019
Uniprot IDs		P46439 Q5T8R2	Q9Y2J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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